Follow the Sex: Influence of Network Structure on the Effectiveness and Cost-Effectiveness of Partner Management Strategies for Sexually Transmitted Infection Control.

ABSTRACT:

Background

It is well established that network structure strongly influences infectious disease dynamics. However, little is known about how the network structure impacts the cost-effectiveness of disease control strategies. We evaluated partner management strategies to address bacterial sexually transmitted infections (STIs) as a case study to explore the influence of the network structure on the optimal disease management strategy.

Methods

We simulated a hypothetical bacterial STI spread through 4 representative network structures: random, community-structured, scale-free, and empirical. We simulated disease outcomes (prevalence, incidence, total infected person-months) and cost-effectiveness of 4 partner management strategies in each network structure: routine STI screeni

SUBMITTER: Kao SZ 

PROVIDER: S-EPMC7428058 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature