Left Ventricular Mass Index Is Associated With Cognitive Function in Middle-Age: Bogalusa Heart Study.

ABSTRACT:

Background

Elevated cardiovascular disease risk factor burden is a recognized contributor to poorer cognitive function; however, the physiological mechanisms underlying this association are not well understood. We sought to assess the potential mediation effect of left ventricular (LV) remodeling on the association between lifetime systolic blood pressure and cognitive function in a community-based cohort of middle-aged adults.

Methods

Nine hundred sixty participants of the Bogalusa Heart Study (59.2% women, 33.8% black, aged 48.4±5.1 years) received 2-dimensional echocardiography to quantify relative wall thickness, LV mass, and diastolic and systolic LV function; and a standardized neurocognitive battery to assess memory, executive functioning, and language processing. Mul

SUBMITTER: Razavi AC 

PROVIDER: S-EPMC7428065 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature