Rh(III)-Catalyzed Cyclopropanation of Unactivated Olefins Initiated by C-H Activation.

ABSTRACT: We have developed a Rh(III)-catalyzed cyclopropanation of unactivated olefins initiated by an alkenyl C-H activation. A variety of 1,1-disubstituted olefins undergo efficient cyclopropanation with a slight excess of alkene stoichiometry. A series of mechanistic interrogations implicate a metal-carbene as an intermediate.

SUBMITTER: Phipps EJT 

PROVIDER: S-EPMC7428168 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature