Unravelling host-pathogen interactions: ceRNA network in SARS-CoV-2 infection (COVID-19).

ABSTRACT: COVID-19 is a lurking calamitous disease caused by an unusual virus, SARS-CoV-2, causing massive deaths worldwide. Nonetheless, explicit therapeutic drugs or clinically approved vaccines are not available for COVID-19. Thus, a comprehensive research is crucially needed to decode the pathogenic tools, plausible drug targets, committed to the development of efficient therapy. Host-pathogen interactions via host cellular components is an emerging field of research in this respect. miRNAs have been established as vital players in host-virus interactions. Moreover, viruses have the capability to manoeuvre the host miRNA networks according to their own obligations. Besides protein coding mRNAs, noncoding RNAs might also be targeted in infected cells and viruses can exploit the host miRNA network

SUBMITTER: Arora S 

PROVIDER: S-EPMC7428439 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature