Relationship Between Dietary Magnesium Intake and Incident Heart Failure Among Older Women: The WHI.

ABSTRACT: Background Women represent a large proportion of the growing heart failure (HF) epidemic, yet data are lacking regarding optimal dietary and lifestyle prevention strategies for them. Specifically, the association between magnesium intake and HF in a multiracial cohort of women is uncertain. Methods and Results We included 97 725 postmenopausal women from the WHI (Women's Health Initiative) observational studies and placebo arms of the hormone trial. Magnesium intake was measured at baseline by a 122-item validated food-frequency questionnaire and stratified into quartiles based on diet only, total intake (diet with supplements), and residual intake (calibration by total energy). Incident hospitalized HF (2153 events, median follow-up 8.1 years) was adjudicated by medical record abstraction

SUBMITTER: Wu WC 

PROVIDER: S-EPMC7428611 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature