Development of a Novel Adult Congenital Heart Disease-Specific Patient-Reported Outcome Metric.

ABSTRACT: Background Patient-reported outcome metrics (PROs) quantify important outcomes in clinical trials and can be sensitive measures of patient experience in clinical practice. Currently, there is no validated disease-specific PRO for adults with congenital heart disease (ACHD). Methods and Results We conducted a preliminary psychometric validation of a novel ACHD PRO. ACHD patients were recruited prospectively from 2 institutions and completed a series of questionnaires, a physician health assessment, and a 6-minute walk test. Participants returned to complete the same questionnaires and assessment 3 months±2 weeks later. We tested the internal consistency and test-retest reliability by comparing responses among clinically stable patients at the 2 study visits. We assessed convergent and diver

SUBMITTER: Cedars AM 

PROVIDER: S-EPMC7428986 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature