Broader adaptive range of sympathetic burst size in response to blood pressure change in older women with greater arterial stiffness.

ABSTRACT:

Key points

In this study, we focused on muscle sympathetic nerve activity (MSNA) burst size and occurrence separately as subcomponents of the sympathetic baroreflex in older adults, and we found that the distribution (variation) of burst size against burst occurrence was greater in women than men. Older women had greater carotid artery stiffness compared with older men, while blood pressure (BP) distribution (variation) was comparable between sexes. Sympathetic baroreflex sensitivity assessed with burst incidence was less sensitive as the carotid artery became stiffer in older men and women, while that assessed with burst area was more sensitive as the carotid artery became stiffer in older women but not in older men. These results help us understand the mechanisms underlying the c

SUBMITTER: Okada Y 

PROVIDER: S-EPMC7429302 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature