Diagnostic accuracy of D-dimer in periprosthetic joint infection: a diagnostic meta-analysis.

ABSTRACT:

Background

Periprosthetic joint infection (PJI) is one of the most devastating complications after total joint replacement (TJA). Up to now, the diagnosis of PJI is still in a dilemma. As a novel biomarker, whether D-dimer is valuable in the diagnosis of PJI remains controversial. This meta-analysis attempts to determine the diagnostic accuracy of D-dimer in PJI.

Methods

Relevant literature was retrieved from PubMed, Embase, Web of Science, and Cochrane Library (from database establishment to April 2020). Literature quality was evaluated using Revman (version 5.3). The random effect model was used in the Stata version 14.0 software to combine sensitivity, specificity, likelihood ratio (LR), diagnostic odds ratio (DOR), summary receiver operating characteristic (SROC) curve,

SUBMITTER: Zhang H 

PROVIDER: S-EPMC7430004 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature