Pericardial fat and its influence on cardiac diastolic function.

ABSTRACT:

Background

Pericardial fat (PF) has been suggested to directly act on cardiomyocytes, leading to diastolic dysfunction. The aim of this study was to investigate whether a higher PF volume is associated with a lower diastolic function in healthy subjects.

Methods

254 adults (40-70 years, BMI 18-35 kg/m², normal left ventricular ejection fraction), with (a)typical chest pain (otherwise healthy) from the cardiology outpatient clinic were retrospectively included in this study. All patients underwent a coronary computed tomographic angiography for the measurement of pericardial fat volume, as well as a transthoracic echocardiography for the assessment of diastolic function parameters. To assess the independent association of PF and diastolic function parameters, multi

SUBMITTER: de Wit-Verheggen VHW 

PROVIDER: S-EPMC7430122 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature