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Water-Dispersible and Biocompatible Iron Carbide Nanoparticles with High Specific Absorption Rate.


ABSTRACT: Magnetic nanoparticles are important tools for biomedicine, where they serve as versatile multifunctional instruments for a wide range of applications. Among these applications, magnetic hyperthermia is of special interest for the destruction of tumors and triggering of drug delivery. However, many applications of magnetic nanoparticles require high-quality magnetic nanoparticles displaying high specific absorption rates (SARs), which remains a challenge today. We report here the functionalization and stabilization in aqueous media of highly magnetic 15 nm iron carbide nanoparticles featuring excellent heating power through magnetic induction. The challenge of achieving water solubility and colloidal stability was addressed by designing and using specific dopamine-based ligands. The result

SUBMITTER: Bordet A 

PROVIDER: S-EPMC7430224 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature