Household representative sample strategy for COVID-19 large-scale population screening.

ABSTRACT: In the advent of COVID-19 pandemic, testing is highly essential to be able to identify, isolate, treat infected persons, and finally curb transmission of this infectious respiratory disease. Group testing has been used previously for various infectious diseases and recently reported for large-scale population testing of COVID-19. However, possible sample dilution as a result of large pool sizes has been reported, limiting testing methods' detection sensitivity. Moreover, the need to sample all individuals prior to pooling overburden the limited resources such as test kits. An alternative proposed strategy where test is performed on pooled samples from individuals representing different households is presented here. This strategy intends to improve group testing method through the reduction

SUBMITTER: Takyi-Williams J 

PROVIDER: S-EPMC7430343 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature