Utilizing drug repurposing against COVID-19 - Efficacy, limitations, and challenges.

ABSTRACT: The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then essentially across the world has been declared a pandemic by the WHO. COVID-19 is caused by a novel virus SARS-CoV2 (2019-nCoV), against which there is currently no vaccine available; and current antiviral therapies have failed, causing a very high mortality rate. Drug repurposing i.e. utilizing an approved drug for different indication, offers a time- and cost-efficient alternative for making new therapies available to patients. Although there are several reports presenting novel approaches to treat COVID-19, still an attentive review of previous scientific literature is essential to overcome their failure to exhibit efficacy. There is an urgent need to provide a comprehensive outlook toward utilizing dr

SUBMITTER: Parvathaneni V 

PROVIDER: S-EPMC7430345 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature