Genetic analysis and emergence of canine parvovirus type 2c in South Eastern Nigeria.

ABSTRACT:

Background

Genetic analysis of canine parvovirus type 2 (CPV-2) variants circulating in South Eastern Nigeria was investigated. The original strain of CPV-2 emerged in 1978, mutated later to CPV-2a and has continued to be evolved.

Aims

To genetically characterize CPV-2 strains detected in dogs in South Eastern Nigeria and to phylogenetically group the viruses with existing sequencing data.

Methods

A total number of 82 rectal swabs were collected and stored in virus transport medium (VTM) from suspected cases of CPV-2 within the study area and were tested with polymerase chain reaction (PCR).

Results

Seventy-nine samples (96.3%) were positive for CPV-2 and sequence analysis of partial VP2 gene of 20 amplicons revealed circulation of CPV-2a (n=4) and CPV-2

SUBMITTER: Ukwueze CS 

PROVIDER: S-EPMC7430366 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature