Low-density lipoprotein cholesterol and all-cause mortality: findings from the China health and retirement longitudinal study.

ABSTRACT:

Objectives

To investigate the relationship between low-density lipoprotein cholesterol (LDL-C) and all-cause mortality among middle-aged and elderly Chinese population.

Design

Prospective cohort study.

Setting

This study used data from the China Health and Retirement Longitudinal Study.

Participants

Middle-aged and elderly participants with complete data were enrolled for a 4-year follow-up of total mortality and plasma levels of LDL-C, including 4981 male respondents and 5529 female respondents.

Results

During a 4-year follow-up, there were 305 and 219 deaths in men and women, respectively. Compared with the first quintile (Q1) of LDL-C, the adjusted HRs (95% CIs) were 0.818 (0.531 to 1.260) for Q2, 0.782 (0.507 to 1.208) for Q3, 0.605 (0.381 to 0.962)

SUBMITTER: Zhou L 

PROVIDER: S-EPMC7430481 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature