Association Between Antecedent Statin Use and Decreased Mortality in Hospitalized Patients with COVID-19.

ABSTRACT: The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known to have anti-inflammatory and antithrombotic properties, have been studied in the setting of other viral infections and ARDS, but their benefit has not been assessed in COVID-19. Thus, we sought to determine whether antecedent statin use is associated with lower in-hospital mortality in patients hospitalized for COVID-19. This is a retrospective analysis of patients admitted with COVID-19 from February 1 ^st through May 12 ^th , 2020 with study period ending on June

SUBMITTER: Gupta A 

PROVIDER: S-EPMC7430584 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature