Dimeric Proanthocyanidins on the Stability of Dentin and Adhesive Biointerfaces.

ABSTRACT: A dentin biomodification strategy with selective proanthocyanidin (PAC)-enriched extracts reinforces dentin and dentin-resin interfaces. Enrichment of the extracts according to the degree of polymerization allows exploration of bioactive principles of PACs and structure-activity relationships. This study investigated the sustained dentin matrix biomodification and dentin-resin bioadhesion of 2 fractions consisting exclusively of B-type PAC dimers with or without a single galloyl motif (specifically, DIMER_G and DIMER_NG) and their precursor material, enriched grape seed extract (e-GSE; Vitis vinifera). The biomodification potential was determined by long-term evaluation of the apparent modulus of elasticity and collagen solubility (hydroxyproline release). Chemic

SUBMITTER: Leme-Kraus AA 

PROVIDER: S-EPMC7431887 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature