CHIME: CMOS-Hosted in vivo Microelectrodes for Massively Scalable Neuronal Recordings.

ABSTRACT: Mammalian brains consist of 10s of millions to 100s of billions of neurons operating at millisecond time scales, of which current recording techniques only capture a tiny fraction. Recording techniques capable of sampling neural activity at high spatiotemporal resolution have been difficult to scale. The most intensively studied mammalian neuronal networks, such as the neocortex, show a layered architecture, where the optimal recording technology samples densely over large areas. However, the need for application-specific designs as well as the mismatch between the three-dimensional architecture of the brain and largely two-dimensional microfabrication techniques profoundly limits both neurophysiological research and neural prosthetics. Here, we discuss a novel strategy for scalable neuron

SUBMITTER: Kollo M 

PROVIDER: S-EPMC7432274 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature