Epigenetic Regulation of Verticillium dahliae Virulence: Does DNA Methylation Level Play A Role?

ABSTRACT: Verticillium dahliae is the etiological agent of Verticillium wilt of olive. The virulence of Defoliating V. dahliae isolates usually displays differences and high plasticity. This work studied whether an epigenetic mechanism was involved in this plasticity. An inverse correlation between virulence and DNA methylation of protein-coding genes was found. A set of 831 genes was selected for their highly consistent inverse methylation profile and virulence in the five studied isolates. Of these genes, ATP-synthesis was highly represented, which indicates that the more virulent D isolates are, the more energy requirements they may have. Furthermore, there were numerous genes in the protein biosynthesis process: genes coding for the chromatin structure, which suggests that epigenet

SUBMITTER: Ramirez-Tejero JA 

PROVIDER: S-EPMC7432615 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature