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ABSTRACT: Background
To evaluate the effect of clinicopathologic factors on the prognosis and fertility outcomes of BOT patients.Methods
We performed a retrospective analysis of BOT patients who underwent surgical procedures in West China Second University Hospital from 2008 to 2015. The DFS outcomes, potential prognostic factors and fertility outcomes were evaluated.Results
Four hundred forty-eight patients were included; 52 recurrences were observed. Ninety-two patients undergoing FSS achieved pregnancy. No significant differences in fertility outcomes were found between the staging and unstaged surgery groups. Staging surgery was not an independent prognostic factor for DFS. Laparoscopy resulted in better prognosis than laparotomy in patients with stage I tumours and a desire for fertility preservation.Conclusion
Patients with BOT fail to benefit from surgical staging. Laparoscopy is recommended for patients with stage I disease who desire to preserve fertility. Physicians should pay more attention to risk of recurrence in patients who want to preserve fertility.
SUBMITTER: Li N
PROVIDER: S-EPMC7433083 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Li Na N Gou Jinhai J Li Lin L Ming Xiu X Hu Ting Wenyi TW Li Zhengyu Z
BMC cancer 20200817 1
<h4>Background</h4>To evaluate the effect of clinicopathologic factors on the prognosis and fertility outcomes of BOT patients.<h4>Methods</h4>We performed a retrospective analysis of BOT patients who underwent surgical procedures in West China Second University Hospital from 2008 to 2015. The DFS outcomes, potential prognostic factors and fertility outcomes were evaluated.<h4>Results</h4>Four hundred forty-eight patients were included; 52 recurrences were observed. Ninety-two patients undergoin ...[more]