Systematic characterization of the branch point binding protein, splicing factor 1, gene family in plant development and stress responses.

ABSTRACT:

Background

Among eukaryotic organisms, alternative splicing is an important process that can generate multiple transcripts from one same precursor messenger RNA, which greatly increase transcriptome and proteome diversity. This process is carried out by a super-protein complex defined as the spliceosome. Specifically, splicing factor 1/branchpoint binding protein (SF1/BBP) is a single protein that can bind to the intronic branchpoint sequence (BPS), connecting the 5' and 3' splice site binding complexes during early spliceosome assembly. The molecular function of this protein has been extensively investigated in yeast, metazoa and mammals. However, its counterpart in plants has been seldomly reported.

Results

To this end, we conducted a systematic characterization of the SF1

SUBMITTER: Zhang KL 

PROVIDER: S-EPMC7433366 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature