Development and validation of a pretreatment nomogram to predict overall survival in gastric cancer.

ABSTRACT:

Background

Pretreatment clinical staging is essential to select therapy. However, there have been no published pretreatment gastric cancer nomograms constructed using pretreatment clinical prognostic factors, including in nonresection patients. We aimed to develop a new pretreatment gastric cancer nomogram for individualized prediction of overall survival (OS).

Methods

The nomogram was developed using data of 5231 Japanese gastric cancer patients, and it was created with a Cox regression model. Fifteen clinical variables, which were obtained at pretreatment, were collected and registered. Data of two independent cohorts of patients from Seoul St. Mary's Hospital (1001 patients), and the University of Verona (389 patients) formed the external validation cohorts. The model was

SUBMITTER: Bando E 

PROVIDER: S-EPMC7433838 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature