Germline whole genome sequencing in pediatric oncology in Denmark-Practitioner perspectives.

ABSTRACT:

Background

With the implementation of a research project providing whole genome sequencing (WGS) to all pediatric cancer patients in Denmark (2016-2019), we sought to investigate healthcare professionals' views on WGS as it was actively being implemented in pediatric oncology.

Methods

Semistructured interviews were carried out with pediatric oncologists, clinical geneticists, and research coordinating nurses (N = 17), followed by content analysis of transcribed interviews. Interviews were supplemented by ethnographic observations on Danish pediatric oncology wards. Additionally, questionnaires were distributed to healthcare professionals concerning when they found it appropriate to approach families regarding WGS. The response rate was 74%.

Results

Healthcare professi

SUBMITTER: Byrjalsen A 

PROVIDER: S-EPMC7434747 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature