A systematic review of ongoing clinical trials in optic pathway gliomas.

ABSTRACT:

Introduction

Optic pathway gliomas (OPGs), also known as Visual Pathway Gliomas, are insidious, debilitating tumours. They are most commonly WHO grade 1 pilocytic astrocytomas and frequently occur in patients with neurofibromatosis type 1. The location of OPGs within the optic pathway typically precludes complete resection or optimal radiation dosing, hence outcomes remain poor compared to many other low-grade gliomas. The aim of this systematic review was to formulate a comprehensive list of all current ongoing clinical trials that are specifically looking at clinical care of OPGs in order to identify trends in current research and provide an overview to guide future research efforts.

Methods

This systematic review was conducted in line with the Preferred Reporting Items fo

SUBMITTER: Hill CS 

PROVIDER: S-EPMC7434789 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature