Features of severe COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Background

To systematically review clinical and biochemical characteristics associated with the severity of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related disease (COVID-19).

Materials and methods

Systematic review of observational studies from PubMed, ISI Web of Science, SCOPUS and Cochrane databases including people affected by COVID-19 and reporting data according to the severity of the disease. Data were combined with odds ratio (OR) and metanalysed. Severe COVID-19 was defined by acute respiratory distress syndrome, intensive care unit admission and death.

Results

We included 12 studies with 2794 patients, of whom 596 (21.33%) had severe disease. A slightly higher age was found in severe vs non-severe disease. We found that preval

SUBMITTER: Del Sole F 

PROVIDER: S-EPMC7435565 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature