Dataset Information

Influences of bovine colostrum on nasal swab microbiome and viral upper respiratory tract infections - A case report.

ABSTRACT: Bovine colostrum has been advocated as a source of immunity against external environmental microorganisms. Recurrent upper respiratory tract infections present a critical public health concern in the developing countries. The present case report was performed to assess the influence of bovine colostrum in preventing recurrent upper respiratory tract infections caused by respiratory viruses in an adult in Jordan in addition to its effect on respiratory microbiome. In conclusion, bovine colostrum was successful in the prevention of upper respiratory tract infections and significantly affected the nasal swab microbiome. This is the first case report investigating the influence of bovine colostrum on the nasal swab microbiome.

SUBMITTER: Alsayed A

PROVIDER: S-EPMC7437540 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Influences of bovine colostrum on nasal swab microbiome and viral upper respiratory tract infections - A case report.

Alsayed Ahmad A Al-Doori Abdulhameed A Al-Dulaimi Abdullah A Alnaseri Abdullah A Abuhashish Juhayna J Aliasin Khaled K Alfayoumi Ibrahim I

Respiratory medicine case reports 20200819

Bovine colostrum has been advocated as a source of immunity against external environmental microorganisms. Recurrent upper respiratory tract infections present a critical public health concern in the developing countries. The present case report was performed to assess the influence of bovine colostrum in preventing recurrent upper respiratory tract infections caused by respiratory viruses in an adult in Jordan in addition to its effect on respiratory microbiome. In conclusion, bovine colostrum ...[more]

PMID: 32839688

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Project description:BackgroundBovine respiratory disease (BRD) is an ongoing health and economic challenge in the dairy and beef cattle industries. Multiple risk factors make an animal susceptible to BRD. The presence of Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis in lung tissues have been associated with BRD mortalities, but they are also commonly present in the upper respiratory tract of healthy animals. This study aims to compare the cattle nasal microbiome (diversity, composition and community interaction) and the abundance of BRD pathogens (by qPCR) in the nasal microbiome of Holstein steers that are apparently healthy (Healthy group, n = 75) or with BRD clinical signs (BRD group, n = 58). We then used random forest models based on nasal microbial community and qPCR results to classify healthy and BRD-affected animals and determined the agreement with the visual clinical signs. Additionally, co-occurring species pairs were identified in visually BRD or healthy animal groups.ResultsCattle in the BRD group had lower alpha diversity than pen-mates in the healthy group. Amplicon sequence variants (ASVs) from Trueperella pyogenes, Bibersteinia and Mycoplasma spp. were increased in relative abundance in the BRD group, while ASVs from Mycoplasma bovirhinis and Clostridium sensu stricto were increased in the healthy group. Prevalence of H. somni (98%) and P. multocida (97%) was high regardless of BRD clinical signs whereas M. haemolytica (81 and 61%, respectively) and M. bovis (74 and 51%, respectively) were more prevalent in the BRD group than the healthy group. In the BRD group, the abundance of M. haemolytica and M. bovis was increased, while H. somni abundance was decreased. Visual observation of clinical signs agreed with classification by the nasal microbial community (misclassification rate of 32%) and qPCR results (misclassification rate 34%). Co-occurrence analysis demonstrated that the nasal microbiome of BRD-affected cattle presented fewer bacterial associations than healthy cattle.ConclusionsThis study offers insight into the prevalence and abundance of BRD pathogens and the differences in the nasal microbiome between healthy and BRD animals. This suggests that nasal bacterial communities provide a potential platform for future studies and potential pen-side diagnostic testing.

Dataset Information

Influences of bovine colostrum on nasal swab microbiome and viral upper respiratory tract infections - A case report.

Publications

Influences of bovine colostrum on nasal swab microbiome and viral upper respiratory tract infections - A case report.

Similar Datasets

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