Genomic Surveillance of Yellow Fever Virus Epizootic in Sao Paulo, Brazil, 2016 - 2018.

ABSTRACT: São Paulo, a densely inhabited state in southeast Brazil that contains the fourth most populated city in the world, recently experienced its largest yellow fever virus (YFV) outbreak in decades. YFV does not normally circulate extensively in São Paulo, so most people were unvaccinated when the outbreak began. Surveillance in non-human primates (NHPs) is important for determining the magnitude and geographic extent of an epizootic, thereby helping to evaluate the risk of YFV spillover to humans. Data from infected NHPs can give more accurate insights into YFV spread than when using data from human cases alone. To contextualise human cases, identify epizootic foci and uncover the rate and direction of YFV spread in São Paulo, we generated and analysed virus genomic data and epizootic case da

SUBMITTER: Hill SC 

PROVIDER: S-EPMC7437926 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature