Association between metabolic syndrome and recurrence of nonmuscle-invasive bladder cancer in older adults.

ABSTRACT:

Background

Nonmuscle-invasive bladder cancer (NMIBC) disproportionately affects older adults who often have coexisting chronic conditions such as metabolic syndrome (MetS). Although prior research suggests that MetS is a risk factor for NMIBC, limited data exists on whether MetS is associated with NMIBC recurrence. Our objective was to evaluate the association between MetS and recurrence in older adults treated for NMIBC.

Methods

We identified 1,485 older (age ≥60 years) NMIBC patients (American Joint Committee on Cancer Stage ≤1) from 2community-based health systems. Using data from the health systems' electronic medical record, MetS was defined as the presence of three of the following: diagnosis codes indicating hypertension, hyperlipidemia, diabetes, or body mass index >

SUBMITTER: Garg T 

PROVIDER: S-EPMC7438276 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature