Pain trajectories of dorsomedial prefrontal intermittent theta burst stimulation versus sham treatment in depression.

ABSTRACT:

Background

Prefrontal repetitive transcranial magnetic stimulation is an established add-on treatment for major depressive disorder and is increasingly feasible with protocols of short duration, such as intermittent theta burst stimulation (iTBS). The most common and limiting side effect is pain at the site of application. Our objective was to investigate how pain develops over time in patients with depression receiving iTBS compared to sham stimulation.

Methods

This is a subsample from a randomized clinical trial. Patients received daily sessions of 2400 pulses of dorsomedial prefrontal iTBS or sham stimulation with transcutaneous electric stimulation during 2 to 3 weeks. After unmasking of treatment allocation, patients receiving sham treatment were offered active iTBS in

SUBMITTER: Malm E 

PROVIDER: S-EPMC7439669 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature