Association between CD24 Ala/Val polymorphism and multiple sclerosis risk: A meta analysis.

ABSTRACT:

Background

The aim of this study was to explore the association between CD24 Ala/Val polymorphism and susceptibility of multiple sclerosis (MS).

Methods

A comprehensive literature search for relevant studies was performed on google scholar, PubMed, Web of science, Embase, the Chinese National Knowledge Infrastructure and the Chinese Biology Medicine. This meta-analysis was conducted using the STATA 11.0 software and the pooled odds ratio with 95% confidence interval was calculated.

Results

Seven case-control studies were included in this meta-analysis. The results showed significant association between CD24 Ala/Val polymorphism and susceptibility to MS. Stratified analysis by areas also showed significant association in Asians. However, no association was found in Eur

SUBMITTER: Yang W 

PROVIDER: S-EPMC7440312 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature