Effect of ventilation rate on recovery after cardiac arrest in a pediatric animal model.

ABSTRACT:

Aims

To assess the impact of two different respiratory rates in hemodynamic, perfusion and ventilation parameters in a pediatric animal model of cardiac arrest (CA).

Methods

An experimental randomized controlled trial was carried out in 50 piglets under asphyxial CA. After ROSC, they were randomized into two groups: 20 and 30 respirations per minute (rpm). Hemodynamic, perfusion and ventilation parameters were measured 10 minutes after asphyxia, just before ROSC and at 5, 15, 30 and 60 minutes after ROSC. Independent medians test, Kruskal-Wallis test and χ2 test, were used to compare continuous and categorical variables, respectively. Spearman's Rho was used to assess correlation between continuous variables. A p-value <0.05 was considered significant.

Results

Arteria

SUBMITTER: Lopez J 

PROVIDER: S-EPMC7440626 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature