Survival implication of lymphadenectomy in patients surgically treated for apparent early-stage uterine serous carcinoma.

ABSTRACT:

Objective

Uterine serous carcinoma (USC) is a rare highly aggressive disease. In the present study, we aimed to investigate the survival implication of the systematic lymphadenectomy in patients who underwent surgery for apparent early-stage USC.

Methods

Consecutive patients with apparent early-stage USC surgically treated at six Italian referral cancer centers were analyzed. A comparison was made between patients who underwent retroperitoneal staging including at least pelvic lymphadenectomy "LND" vs. those who underwent hysterectomy alone "NO-LND". Baseline, surgical and oncological outcomes were analyzed. Kaplan- Meier curves were calculated for disease-free survival (DFS) and disease-specific survival (DSS). Associations were evaluated with Cox proportional hazard regres

SUBMITTER: Casarin J 

PROVIDER: S-EPMC7440990 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature