Comparative molecular investigation of the potential inhibitors against SARS-CoV-2 main protease: a molecular docking study.

ABSTRACT: Recent outbreak of novel coronavirus and its rapid pandemic escalation in all over the world has drawn the attention to urgent need for effective drug development. However, due to prolonged vaccine and drug development procedure against a newly emerged devastating SARS-CoV-2 virus pathogen, repurposing of existing potential pertinent drug molecules would be preferable strategy to reduce mortality immediately and further development of new drugs to combat overall global Covid-19 crisis in all over the world. Herein, we have filtered 23 prospective drug candidates through literature review. Assessing evidences from molecular docking studies, it was clearly seen that, Epirubicin, Vapreotida, and Saquinavir exhibited better binding affinity against SARS-CoV-2 Main Protease than other drug mole

SUBMITTER: Khan MA 

PROVIDER: S-EPMC7441768 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature