Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor^®.

ABSTRACT: Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C-F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols.

SUBMITTER: Gonzalez-Esguevillas M 

PROVIDER: S-EPMC7441851 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature