Surgical Resection of Pheochromocytomas and Paragangliomas is Associated with Lower Cholesterol Levels.

ABSTRACT:

Background

Catecholamine excess in patients with pheochromocytomas or paragangliomas (PPGLs) can lead to hypertension, diabetes and hyperlipidemia. The aim was to investigate the prevalence of hyperlipidemia and the effect of surgical resection.

Methods

One hundred and thirty-two patients with PPGLs underwent an operation at the National Institutes of Health from 2009 to 2016, of which 54 patients met the inclusion criteria. Clinical demographics, BMI, genetic mutations, tumor size, perioperative catecholamine levels and perioperative lipid panels were retrospectively reviewed. Spearman correlation between catecholamines and lipid levels was evaluated. Paired Wilcoxon and paired t test were used to analyze differences in pre- and postoperative lipid levels.

Results

Pr

SUBMITTER: Good ML 

PROVIDER: S-EPMC7442156 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature