Perspective: Dietary Biomarkers of Intake and Exposure-Exploration with Omics Approaches.

ABSTRACT: While conventional nutrition research has yielded biomarkers such as doubly labeled water for energy metabolism and 24-h urinary nitrogen for protein intake, a critical need exists for additional, equally robust biomarkers that allow for objective assessment of specific food intake and dietary exposure. Recent advances in high-throughput MS combined with improved metabolomics techniques and bioinformatic tools provide new opportunities for dietary biomarker development. In September 2018, the NIH organized a 2-d workshop to engage nutrition and omics researchers and explore the potential of multiomics approaches in nutritional biomarker research. The current Perspective summarizes key gaps and challenges identified, as well as the recommendations from the workshop that could serve as a gui

SUBMITTER: Maruvada P 

PROVIDER: S-EPMC7442414 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature