Crucial laboratory parameters in COVID-19 diagnosis and prognosis: An updated meta-analysis.

ABSTRACT:

Introduction and objectives

Common laboratory parameters are crucial in aiding coronavirus disease 2019 (COVID-19) case detection. This study aimed to determine the differences between laboratory parameters in (1) COVID-19 versus non-COVID-19 pneumonia, and (2) severe versus non-severe COVID-19 cases.

Methods

Studies were collected until March 2020, and retrieved parameters include leukocyte, neutrophil, thrombocyte, and lymphocyte counts in addition to C-reactive protein (CRP), procalcitonin (PCT) and D-dimer levels. In the presence of heterogeneity, the random-effect model (REM) was used instead of the fixed-effect model (FEM).

Results

Seven studies in the first analysis showed significantly lower leukocyte, neutrophil and platelet counts in COVID-19 pneumonia (SMD 

SUBMITTER: Soraya GV 

PROVIDER: S-EPMC7442896 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature