Ontology highlight
ABSTRACT:
SUBMITTER: Nolting S
PROVIDER: S-EPMC7443617 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Nölting Svenja S Grossman Ashley A Pacak Karel K
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20180920 2-03
Phaeochromocytomas (PCC) and paragangliomas (PGL) are rare tumours arising from the chromaffin cells of the adrenal medulla (PCC) or the paraganglia located outside the adrenal gland (PGL). However, their incidence is likely to be underestimated; around 10% of all PCC/PGL are metastatic, with higher metastatic potential of PGLs compared to PCCs. If benign, surgery is the treatment of choice, but if metastatic, therapy is challenging. Here we review the currently existing therapy options for meta ...[more]