Comorbidity within mental disorders: a comprehensive analysis based on 145 990 survey respondents from 27 countries.

ABSTRACT: AIMS:Epidemiological studies indicate that individuals with one type of mental disorder have an increased risk of subsequently developing other types of mental disorders. This study aimed to undertake a comprehensive analysis of pair-wise lifetime comorbidity across a range of common mental disorders based on a diverse range of population-based surveys. METHODS:The WHO World Mental Health (WMH) surveys assessed 145 990 adult respondents from 27 countries. Based on retrospectively-reported age-of-onset for 24 DSM-IV mental disorders, associations were examined between all 548 logically possible temporally-ordered disorder pairs. Overall and time-dependent hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Cox proportional hazards models. Absolute risks were estimat

SUBMITTER: McGrath JJ 

PROVIDER: S-EPMC7443806 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature