Early stage colon cancer: Current treatment standards, evolving paradigms, and future directions.

ABSTRACT: Colon cancer continues to be one of the leading causes of mortality and morbidity throughout the world despite the availability of reliable screening tools and effective therapies. The majority of patients with colon cancer are diagnosed at an early stage (stages I to III), which provides an opportunity for cure. The current treatment paradigm of early stage colon cancer consists of surgery followed by adjuvant chemotherapy in a select group of patients, which is directed at the eradication of minimal residual disease to achieve a cure. Surgery alone is curative for the vast majority of colon cancer patients. Currently, surgery and adjuvant chemotherapy can achieve long term survival in about two-thirds of colon cancer patients with nodal involvement. Adjuvant chemotherapy is recommended f

SUBMITTER: Chakrabarti S 

PROVIDER: S-EPMC7443846 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature