3D-Printed Microfluidic Device with In-line Amperometric Detection that Also Enables Multi-Modal Detection.

ABSTRACT: Microfluidic amperometric detectors often include a reservoir to house auxiliary and reference electrodes, making subsequent detection downstream challenging. Here, we present an in-line microfluidic device with amperometric detection that incorporates a three-electrode set-up, made possible by threading electrodes into a 3D-printed flow cell. The electrodes consist of a commercially available threaded reference electrode and electrodes fabricated in commercially available fittings. This approach centers the working electrode in the fluidic channel enabling the use of a pillar working electrode that is shown to increase sensitivity, as compared to a traditional thin-layer electrode. In addition, the working and auxiliary electrodes can be directly opposed, with this configuration leading t

SUBMITTER: Hayter EA 

PROVIDER: S-EPMC7444025 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature