Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction.

ABSTRACT:

Background

We previously reported the results of a trial of prenatal vitamin D supplementation to prevent asthma and recurrent wheeze in young children, which suggested that supplementation provided a protective effect at the age of 3 years. We followed the children through the age of 6 years to determine the course of asthma and recurrent wheeze.

Methods

In this follow-up study, investigators and participants remained unaware of the treatment assignments through the children's sixth birthday. We aimed to determine whether, when maternal levels of 25-hydroxyvitamin D were taken into account, children born to mothers who had received 4400 IU of vitamin D₃ per day during pregnancy (vitamin D group) would have a lower incidence of asthma and recurrent wheeze at the a

SUBMITTER: Litonjua AA 

PROVIDER: S-EPMC7444088 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature