Correlations between molecular structure and biological activity in "logical series" of dietary chromone derivatives.

ABSTRACT: The research was conducted in the "logical series" of seven ligands: chromone, flavone, 3-hydroxyflavone, 3,7-dihydroxyflavone, galangin, kaempferol and quercetin. Each subsequent ligand differs from the previous one, among others by an additional hydroxyl group. The studied chromone derivatives are plant secondary metabolites which play an important role in growth, reproduction, and resistance to pathogens. They are important food ingredients with valuable pro-health properties. The studies of the relationships between their molecular structure and biological activity facilitate searching for new chemical compounds with important biological properties not by trial and error, but concerning the impact of specific changes in their structure on the compound properties. Therefore several pect

SUBMITTER: Lewandowski W 

PROVIDER: S-EPMC7444502 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature