Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009-2018.

ABSTRACT: We examined Massachusetts tuberculosis surveillance data from to 2009 to 2018. Of 1533 culture-confirmed cases, 190 (12.4%) demonstrated resistance to isoniazid including 32 (2.1%) with rifampin resistance. In multivariable analysis, isoniazid resistance increased significantly over time (per-year odds ratio = 1.07, 95% confidence interval = 1.01-1.13, P = .018) and was associated with younger age, foreign birth, and prior tuberculosis treatment.

SUBMITTER: Eddy JJ 

PROVIDER: S-EPMC7444736 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature