J-shaped association between fasting blood glucose levels and COVID-19 severity in patients without diabetes.

ABSTRACT:

Aims

Coronavirus disease 2019 (COVID-19) has become a recognized worldwide pandemic. Researchers now know that mortality from COVID-19 can be reduced through early prevention measures. This retrospective, multi-centered study of 293 COVID-19 patients without diabetes explores the association between fasting blood glucose (FBG) levels and the risk of COVID-19 disease progression, with the goal of providing clinical evidence for glycemic targets in patients.

Methods

The multivariate stepwise binary logistic regression analysis was used to test the dose-response effects of FBG levels on the risk of severe and critical condition in COVID-19 patients.

Results

FBG levels were plotted in quintiles with set at <4.74, 4.74-5.21, 5.21-5.78, 5.78-7.05, and ≧7.05 mmol/L. The cons

SUBMITTER: Zhu B 

PROVIDER: S-EPMC7445136 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature