Prevalence and Distribution Characteristics of bla_KPC-2 and bla_NDM-1 Genes in Klebsiella pneumoniae.

ABSTRACT:

Background

Carbapenem-resistant Klebsiella pneumoniae infections have caused major concern and posed a global threat to public health. As bla_KPC-2 and bla_NDM-1 genes are the most widely reported carbapenem resistant genes in K. pneumonia, it is crucial to study the prevalence and geographical distribution of these two genes for further understanding of their transmission mode and mechanism.

Purpose

Here, we investigated the prevalence and distribution of bla_KPC-2 and bla_NDM-1 genes in carbapenem-resistant K. pneumoniae strains from a tertiary hospital and from 1579 genomes available in the NCBI database, and further analyzed the possible core structure of bla_KPC-2 o

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7445519 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature