Investigation of the Relationship between MR-Based Supraclavicular Fat Fraction and Thyroid Hormones.

ABSTRACT:

Purpose

Brown adipose tissue (BAT) plays a potential role in energy and glucose metabolism in humans. Thyroid hormones (TH) are main regulators of BAT development and function. However, it remains unknown how the magnetic resonance (MR)-based proton density fat fraction (PDFF) of supraclavicular adipose tissue used as a surrogate marker for BAT presence relates to TH. Therefore, the purpose of this analysis was to investigate the relationship between supraclavicular PDFF and serum levels of TH.

Methods

In total, 96 adult volunteers from a large cross-sectional study who underwent additional MR examination of the neck and pelvis were included in this analysis. Segmented PDFF maps of the supraclavicular and gluteal subcutaneous adipose tissue were generated. Delta PDFF was cal

SUBMITTER: Junker D 

PROVIDER: S-EPMC7445585 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature