Comparison of radiographer interobserver image registration variability using cone beam CT and MR for cervix radiotherapy.

ABSTRACT:

Objectives

The aim of this study was to assess the consistency of therapy radiographers performing image registration using cone beam computed tomography (CBCT)-CT, magnetic resonance (MR)-CT, and MR-MR image guidance for cervix cancer radiotherapy and to assess that MR-based image guidance is not inferior to CBCT standard practice.

Methods

10 patients receiving cervix radiation therapy underwent daily CBCT guidance and magnetic resonance (MR) imaging weekly during treatment. Offline registration of each MR image, and corresponding CBCT, to planning CT was performed by five radiographers. MR images were also registered to the earliest MR interobserver variation was assessed using modified Bland-Altman analysis with clinically acceptable 95% limits of agreement (LoA) defined

SUBMITTER: Rodgers J 

PROVIDER: S-EPMC7446016 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature