A cross-sectional nationwide survey of congenital and infantile nephrotic syndrome in Japan.

ABSTRACT:

Background

Congenital nephrotic syndrome (CNS) and infantile nephrotic syndrome (INS) cause substantial morbidity and mortality. In Japan, there is a lack of knowledge regarding the characteristics of CNS and INS. This study aimed to clarify the characteristics of CNS and INS in Japan.

Methods

This cross-sectional nationwide survey obtained data from 44 institutions in Japan managing 92 patients with CNS or INS, by means of two survey questionnaires sent by postal mail. Patients aged < 16 years by 1 April 2015, with a diagnosis of CNS or INS, were included in this study. The primary outcome was end-stage kidney disease.

Results

A total of 83 patients with CNS or INS were analyzed. The most frequent disease type was non-Finnish (60.2%); 33 patients (39.8%) had Finnish

SUBMITTER: Hamasaki Y 

PROVIDER: S-EPMC7446144 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature