Normalization of reduced functional connectivity after revascularization of asymptomatic carotid stenosis.

ABSTRACT: Internal carotid artery stenosis is a risk factor for ischemic stroke. Even in the absence of visible structural brain changes, patients with asymptomatic stenosis are prone to cognitive impairment. On a neuronal level, it was suggested that stenosis may lead to disturbed functional brain connectivity. If so, carotid revascularization should have an effect on hypothesized brain network disturbances. We studied functional connectivity in a motor network by resting-state electroencephalography in 12 patients with high grade asymptomatic carotid stenosis before and after interventional or surgical revascularization as compared to 23 controls. In patients with stenosis, functional connectivity of neural oscillations was significantly decreased prior and improved returning to normal connectivit

SUBMITTER: Quandt F 

PROVIDER: S-EPMC7446560 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature