Disease-Modifying Therapies During the COVID-19 Outbreak: A Narrative Review of International and National Recommendations.

ABSTRACT:

Background

Managing multiple sclerosis (MS) during the novel coronavirus disease 2019 (COVID-19) pandemic is a challenge due to the lack of evidence from clinical studies. Disease-modifying therapies (DMTs) may affect the immune response and subsequently alter the risk of COVID-19 infections.

Methods

A literature search was conducted on the MEDLINE, Embase, and Cochrane databases. A focused Google search was also performed. Recommendations regarding the use of DMTs during the COVID-19 outbreak from national and international MS/neurology societies were identified and reviewed.

Results

The review included 16 recommendations from international and national MS organizations. All recommendations are based on expert opinions. The recommendations regarding DMT initiation an

SUBMITTER: Thakolwiboon S 

PROVIDER: S-EPMC7446628 | biostudies-literature | 2020 Jul-Aug

REPOSITORIES: biostudies-literature